Standardization of the modified Rodnan skin score for use in clinical trials of systemic sclerosis.

نویسندگان

  • Dinesh Khanna
  • Daniel E Furst
  • Philip J Clements
  • Yannick Allanore
  • Murray Baron
  • Lazlo Czirjak
  • Oliver Distler
  • Ivan Foeldvari
  • Masataka Kuwana
  • Marco Matucci-Cerinic
  • Maureen Mayes
  • Thomas Medsger
  • Peter A Merkel
  • Janet E Pope
  • James R Seibold
  • Virginia Steen
  • Wendy Stevens
  • Christopher P Denton
چکیده

The modified Rodnan skin score (mRSS) is a measure of skin thickness and is used as a primary or secondary outcome measure in clinical trials of systemic sclerosis (scleroderma). This state-of-art review provides a historical perspective of the development of the mRSS, summarizes the performance of mRSS as an outcome measure, provides guidance on assessing mRSS, and makes recommendations for incorporation of the mRSS into clinical trials.

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عنوان ژورنال:
  • Journal of scleroderma and related disorders

دوره 2 1  شماره 

صفحات  -

تاریخ انتشار 2017